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1.
Bol. Hosp. Viña del Mar ; 73(2): 52-53, 2017.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1398295

RESUMO

El eritema ab igne es una enfermedad cutánea inusual causada por la exposición crónica de la piel al calor en niveles menores de los necesarios para que ocurra una quemadura. Clínicamente se caracteriza por la presencia de telangiectasias reticuladas e hiperpigmentación de la piel. Su sitio de aparición típico es la zona anterior de los muslos, habitualmente en mujeres que se exponen a una fuente cercana de calor. No existe tratamiento efectivo descrito en la literatura actual y su progresión solo puede prevenirse mediante la eliminación de la exposición al calor. Presentamos un caso de una mujer de 50 años con antecedentes de esclerosis múltiple y psoriasis, que consultó por mácula hiperpigmentada e indolora localizada en región anterior de ambos muslos, de un mes de evolución, que apareció luego de la aplicación de almohadilla térmica por 2 semanas en zona descrita. Al examen físico destacaba la presencia de mácula hiperpigmentada de bordes difuminados, aspecto reticular, color marrón rojizo oscuro, localizada en región anterior de ambos muslos. Se realizó diagnóstico clínico de eritema ab igne, indicándose suspensión del uso de almohadilla térmica. No se indicó manejo específico. Actualmente persiste con hiperpigmentación.


Erythema ab igne is an unusual skin disease caused by chronic exposure to heat at levels too low to cause burns. It is characterized clinically by reticulated telangiectasias and hyperpigmentation of the skin. It is typically seen in anterior thighs, usually in women exposed to a close source of heat. No effective treatment has been described in the literature and progression can be prevented only by suspending the exposure to heat. We present the case of a 50 year old woman with multiple sclerosis and psoriasis who complained of painless hyperpigmented macules on both anterior thighs of one month duration after using a thermal cushion on the region for two weeks. She had dark reddish brown hyper-pigmented, reticulated macules with diffuse borders on each anterior thigh. Erythema ab igne was diagnosed and the use of the thermal cushion was discontinued. No specific treatment was given. The hyperpigmentation persisted.

2.
Rev. chil. dermatol ; 33(3): 93-96, 2017. tab, ilus
Artigo em Espanhol | LILACS | ID: biblio-965059

RESUMO

La acropaquia es un trastorno que puede presentarse en forma aislada o formar parte del síndrome de osteoartropatía hipertrófica, entidad caracterizada por periostosis, dolor articular y acropaquia. Cuando este síndrome es causado por una mutación genética específica, se denomina osteoartropatía hipertrófica primaria. Este raro desorden hereditario se asocia, además, a alteraciones dermatológicas típicas, como hiperseborrea, acné, engrosamiento de pliegues faciales, entre otras. Una asociación rara vez descrita es la queratodermia palmoplantar. Se presenta el caso de una mujer de 46 años con osteoartropatía hipertrófica primaria asociada a queratodermia palmoplantar que asistió a la unidad de dermatología del Hospital Gustavo Fricke, Viña del Mar, Chile.


Clubbing is a disorder that can be an isolated finding or be part of the hypertrophic osteoarthropathy syndrome, an entity characterized by periostosis, joint pain and clubbing. When this syndrome is caused by a specific genetic mutation, it is called primary hypertrophic osteoarthropathy. This rare hereditary disorder is also associated with typical dermatological findings, such as hyperseborrhea, acne and facial feature coarsening. An association rarely described is palmoplantar keratoderma. We present the case of a 46-year-old woman with primary hypertrophic osteoarthropathy and palmoplantar keratoderma who came to the dermatology unit of Gustavo Fricke Hospital, Viña del Mar, Chile.


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Osteoartropatia Hipertrófica Primária/diagnóstico , Osteoartropatia Hipertrófica Primária/etiologia , Ceratodermia Palmar e Plantar/complicações
3.
Memorandum ; 31: 206-217, out. 2016.
Artigo em Espanhol | LILACS | ID: biblio-914657

RESUMO

Desde la aproximación fenomenológica que realiza Edith Stein para la comprensión de la estructura óntica y dinamismo de la acción propiamente humana, se puede considerar la empatía como un acto propio de la persona, el cual está presente en la constitución del individuo psicofísico, y es desde donde se establece el dinamismo perfectivo de ésta. Dando lugar así, a la comprensión de la persona como un ser-con-los-demás, desde donde se establecerán las bases para una ética de la persona considerada en su ser relacional, eludiendo cualquier posible individualismo. La persona al ser una estructura abierta, abierta hacia dentro y hacia fuera, hacia sí mismo y hacia el otro, permite la fundamentación de un ethos relacional, del Yo-Tú, del que emerge el nosotros, y por tanto una comprensión más acabada del bien común.(AU)


From the phenomenological approach that Edith Stein proposed, for understanding the ontological structure and dynamism of human action, empathy can be considered as an act of the person, which is present in the constitution of the Psycho-physical Individual, and establish the perfective dynamism of the person. Leading to the understanding of the person as a being - with -others, from where establishes the basis of an ethic that consider the individual as a relational being, avoiding any possible individualism. The person that is an open structure, open inward and outward, toward himself and toward the other , allows the foundation of a relational ethos, and ethos of the I-Thou, from which emerges the "us?, and a better understanding of the common good.(AU)


Assuntos
Constituição e Estatutos , Empatia , Ética , Psicologia
4.
Biol. Res ; 41(3): 289-301, 2008. ilus, tab, graf
Artigo em Inglês | LILACS | ID: lil-511919

RESUMO

Carotenoids are synthesized in prokaryotic and eukaryotic organisms. In plants and algae, these lipophilic molecules possess antioxidant properties acting as reactive oxygen species scavengers and exert functional roles in hormone synthesis, photosynthesis, photomorphogenesis and in photoprotection. During the past decade almost all carotenogenic genes have been identified as a result of molecular, genetic and biochemical approaches utilizing Arabidopsis thaliana as the model system. Studies carried out in leaves and fruits of A. thaliana and tomato determined that light regulates carotenoid biosynthesis preferentially through the modulation of carotenogenic gene transcription. In this work we showed for the first time that light induces accumulation of psy 1, pds and zds2 transcripts in leaves of Daucus carota (carrot), a novel plant model. In addition, modified roots of carrots exposed to light accumulate zdsl, whereas the pds gene is highly repressed, suggesting that some carotenogenic genes, which are expressed in roots, are regulated by light. Additionally, light negatively regulates the development of the modified carrot root in a reversible manner. Therefore, this suggests that light affects normal growth and carotenogenic gene expression in the modified root of carrot plants. The molecular insight gained into the light-regulated expression of carotenoid genes in this and other model systems will facilitate our understanding of the regulation of carotenoid biosynthesis to improve the prospects for the metabolic engineering of carotenoid production in plants.


Assuntos
Carotenoides/genética , Daucus carota/genética , Regulação da Expressão Gênica de Plantas/genética , Luz , Modelos Genéticos , Carotenoides/biossíntese , Daucus carota/metabolismo , Regulação da Expressão Gênica de Plantas/efeitos da radiação , Reação em Cadeia da Polimerase Via Transcriptase Reversa
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